Some HLA-B*57 subtypes are associated with the rate of illness progressions in HIV-1 infected patients, particularly B*5701 allele in Caucasians and B*5703 allele in Africans populations. The presence of these alleles is strongly associated with hypersensitivity related with ABACAVIR administration/treatment.
HLA-B*57 is also related with HCV infection and psoriases susceptibility.
This kit contains typing plates with dried primer mix and PCR Master Mix for rapid screening of HLA-B*57 gene.
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