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PAI 4G5 Box 1.0
Typing kit for PAI 4G5 mutation
Ref. GB.6210
 
The PAI-1 gene contains a polymorphism (deletion/insertion) in the promoter region at position -675 (4G/5G). This polymorphism has been associated to various pathologies. The genotype 4G/4G reflects the inability of PAI-1 bind to transcriptional suppressor protein.

This condition results in a high transcription molecular. The variation in fibrin degradation leads to a state of hypercoagulability and contributes to the development of vascular complications.

This kit contains typing plates with dried primers mixes and PCR Master Mix for typing of polymorphism 4G5 of PAI-1 gene.
 
Nš of Typings 24 48
 
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