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Products
| MTHFR Box 2.0 |
| Typing kit for MTHFR C677T and A1298C mutations |
| Ref. GB.0111 |
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Mutations in MTHFR gene are the most common genetic cause of hyperhomocysteinaemia. Some mutation in the coding region of MTHFR gene, such as position 677 (MTHFR C677T) and 1298 (MTHFR A1298C), are responsible for the increase of homocysteine in bloodstream.
This change in the gene sequence, results in the substitution of valine for alanine in the catalytic domain of the enzyme (codon 222) resulting in an enzyme thermolabile and less active.
This kit contains typing strips with dried primers mixes and PCR Master Mix for typing of polymorphisms C677T and A1298C of MTHFR gene. |
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| Nº of Typings 24 48 |
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