Mass spectrometry is a
powerful analytical technique that is used to identify and quantify
compounds, and to elucidate the structure and chemical properties of
molecules.
The Unit is specialized in
-identification and
quantification of proteins from simple and complex samples,
-identification and
quantification of post-translational modifications,
-identification and
quantification of drugs and metabolites.
We also aim to identify
biomarkers through proteomics and metabolomics techniques with the
purpose of developing new prognosis and diagnosis methods, in
collaboration with other R&D units at CNC and Biocant and external
partners through our excellence networks.
This unit is equipped with state of the art
technology for:
-uni- and bi-dimensional separation of drugs,
metabolites, peptides and digested proteins from complex samples by
capillary- to analytical-HPLC;
-mass spectrometry identification and quantification
using distinct sample ionization and scan methods, in an hybrid
instrument that takes advantage of the selectivity provided by the
triple quadrupole and the sensitivity of the ion-trap.
4000 QTRAP mass spectrometer
was acquired with founds from "Programa Nacional de Reequipamento
Cientifico"
and the CNC is
member of the Portuguese National Mass Spectrometry Network
Request information
Service Request
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All samples
submitted to the Unit will be processed in accordance with
the
Facility Policy and Users
fees
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